F11R Antikörper (C-Term)

Produktnummer ABIN401517

Produktdetails anti-F11R Antikörper

Target: F11R (F11 Receptor (F11R))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: c-QPSARSEGEF KQTS

Spezifität: This antibody detects CD321/JAM1 (C-term).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Pig.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C-Terminus of the protein sequence according to NP_058642.1. Genename: F11R

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit Dilution: 1/2000. Western blot: 0.3-2 μg/mL. Approx 38 kDa band observed in Human Peripheral BloodMononucleocyte lysates (calculated MW of 32.8 kDa according to NP_058642.1). Theobserved molecular weight corresponds to earlier findings with different antibodies fromother commercial sources.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: CD321 / JAM1 (F11R Produkte)

Synonyme: CD321 antikoerper, JAM antikoerper, JAM1 antikoerper, JAMA antikoerper, JCAM antikoerper, KAT antikoerper, PAM-1 antikoerper, 9130004G24 antikoerper, AA638916 antikoerper, ESTM33 antikoerper, JAM-1 antikoerper, JAM-A antikoerper, Jcam antikoerper, Jcam1 antikoerper, Ly106 antikoerper, Jam1 antikoerper, F11 receptor antikoerper, F11R antikoerper, F11r antikoerper

Hintergrund: Junctional Adhesion Molecule 1 (JAM1) seems to plays a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

Gen-ID: 50848

NCBI Accession: NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization