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F11R Antikörper (C-Term)

F11R Reaktivität: Human, Maus, Ratte ELISA, ICC, IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261639
$390.77
Zzgl. Versandkosten $45.00
Lieferung in 8 bis 9 Werktagen
  • Target Alle F11R Antikörper anzeigen
    F11R (F11 Receptor (F11R))
    Bindungsspezifität
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 70
    • 38
    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 52
    • 15
    • 15
    • 7
    • 2
    Kaninchen
    Klonalität
    • 53
    • 35
    Polyklonal
    Konjugat
    • 46
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser F11R Antikörper ist unkonjugiert
    Applikation
    • 51
    • 25
    • 18
    • 16
    • 14
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
    Spezifität
    JAM1 Antibody detects endogenous levels of total JAM1.
    Homologie
    Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human JAM1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200 IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    F11R (F11 Receptor (F11R))
    Andere Bezeichnung
    F11R (F11R Produkte)
    Synonyme
    CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1, 9130004G24, AA638916, ESTM33, JAM-1, JAM-A, Jcam, Jcam1, Ly106, Jam1, F11 receptor, F11R, F11r
    Hintergrund

    Description: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).

    Gene: F11R

    Molekulargewicht
    33kDa
    Gen-ID
    50848
    UniProt
    Q9Y624
    Pathways
    Cell-Cell Junction Organization
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