F11R Antikörper (AA 30-238)
Kurzübersicht für F11R Antikörper (AA 30-238) (ABIN3021823)
Target
Alle F11R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-238
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Sequenz
- TVHSSEPEVR IPENNPVKLS CAYSGFSSPR VEWKFDQGDT TRLVCYNNKI TASYEDRVTF LPTGITFKSV TREDTGTYTC MVSEEGGNSY GEVKVKLIVL VPPSKPTVNI PSSATIGNRA VLTCSEQDGS PPSEYTWFKD GIVMPTNPKS TRAFSNSSYV LNPTTGELVF DPLSASDTGE YSCEARNGYG TPMTSNAVRM EAVERNVGV
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
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- F11R (F11 Receptor (F11R))
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Andere Bezeichnung
- F11R
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Hintergrund
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Blood,F11R
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Molekulargewicht
- 27 kDa/32 kDa
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Gen-ID
- 50848
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UniProt
- Q9Y624
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Pathways
- Cell-Cell Junction Organization
Target
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