WNT4 Antikörper (C-Term)

Produktnummer ABIN390635

Produktdetails anti-WNT4 Antikörper

Target: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Bindungsspezifität: AA 242-269, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This WNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the C-terminal region of human WNT4.

Klon: RB19966

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-WNT4 Antikörper (ABIN390635)

Beyer, Schramm, Akhmetshina, Dees, Kireva, Gelse, Sonnylal, de Crombrugghe, Taketo, Distler, Schett, Distler: "?-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis." in: Annals of the rheumatic diseases, Vol. 71, Issue 5, pp. 761-7, (2012) (PubMed).

Details zu WNT4

Target: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Andere Bezeichnung: WNT4 (WNT4 Produkte)

Synonyme: CG4698 antikoerper, DWnt-4 antikoerper, DWnt4 antikoerper, Dm DWnt4 antikoerper, Dmel\\CG4698 antikoerper, Dwnt4 antikoerper, Wnt antikoerper, Wnt-4 antikoerper, anon-EST:Liang-2.4 antikoerper, clone 2.4 antikoerper, wnt-4 antikoerper, wnt4 antikoerper, SERKAL antikoerper, WNT-4 antikoerper, Xwnt4 antikoerper, xwnt-4 antikoerper, zgc:136737 antikoerper, Wnt family member 4 antikoerper, Wnt oncogene analog 4 antikoerper, wingless-type MMTV integration site family, member 4 antikoerper, wingless-type MMTV integration site family member 4 S homeolog antikoerper, wingless-type MMTV integration site family, member 4a antikoerper, WNT4 antikoerper, Wnt4 antikoerper, wnt4.S antikoerper, wnt4a antikoerper

Hintergrund: The WNT family consists of secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. It play a concerted role in both the control of female development and the prevention of testes formation.

Molekulargewicht: 39052

Gen-ID: 54361

NCBI Accession: NP_110388

UniProt: P56705

Pathways: WNT Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cell-Cell Junction Organization, Tube Formation