The antibody detects: Human MMP-3 Does not cross react to human MMP-1, MMP-2 or MMP-9 To insure lot-to-lot consistency, each batch of product is tested by ELISA to conform with the characteristics of a standard reference reagent.
MMP3
Reaktivität: Human
ELISA, IP
Wirt: Maus
Monoclonal
4C11
unconjugated
Applikationshinweise
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Probenmenge
1 mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Protect conjugated products from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to brea kDaown connective tissue. MMP-3, also known as stomelysin-1 and transin, belongs to the stromelysin group of MMP's which also includes MMP-10. MMP-3 has shown direct and indirect substrate specificity to collagens III, IV, V and IX, gelatins, fibronectin, fibrinogen, plasminogen, proteoglycans, elastin, casein, entactin, myelin basic protein, IL-1b, serum amyloid A, TIMP-2, MMP-1, MMP-7, MMP-8, MMP-9, and MMP-13.