CRHR1 Antikörper (Internal Region)

Produktnummer ABIN374874

Produktdetails anti-CRHR1 Antikörper

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Bindungsspezifität: AA 107-117, Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CRHR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Sequenz: C-NEEKKSKVHY H

Spezifität: This antibody detects CRHR1.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_004373.2 Genename: CRHR1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 60-70 kDa band observed in human brain (cerebellum)and human colon lysates (calculated MW of 47.0 kDa according to NP_004373.2). Theobserved molecular weight corresponds to earlier findings in literature with differentantibodies (Xu et al, Mol Pharmacol.2001 Mar,59(3): 485-92, PMID: 11179443) . Immunofluorescence: 2 μg/mL when incubated at 4 °C for 40h (mouse brain).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CRHR1

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Andere Bezeichnung: CRHR1 (CRHR1 Produkte)

Synonyme: CRF-R antikoerper, CRF-R-1 antikoerper, CRF-R1 antikoerper, CRF1 antikoerper, CRFR-1 antikoerper, CRFR1 antikoerper, CRH-R-1 antikoerper, CRH-R1 antikoerper, CRH-R1h antikoerper, CRHR antikoerper, CRHR1L antikoerper, CRHR1f antikoerper, Crhr antikoerper, crhr1 antikoerper, crhr1-A antikoerper, CRHR1 antikoerper, CRHR1-IT1-CRHR1 antikoerper, MGC57346-CRHR1 antikoerper, corticotropin releasing hormone receptor 1 antikoerper, corticotropin releasing hormone receptor 1, gene 2 S homeolog antikoerper, corticotropin-releasing factor receptor 1 antikoerper, LINC02210-CRHR1 readthrough antikoerper, CRHR1 antikoerper, Crhr1 antikoerper, crhr1.2.S antikoerper, LOC610380 antikoerper, LOC100065598 antikoerper, LINC02210-CRHR1 antikoerper, crhr1 antikoerper

Hintergrund: CRF1 is a receptor for corticotropin releasing factor. It shows high affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.Synonyms: CRF-R, CRF1, CRFR, CRFR1, CRH-R 1, CRHR, CRHR-1, Corticotropin-releasing factor receptor 1, Corticotropin-releasing hormone receptor 1

Gen-ID: 1394

NCBI Accession: NP_001138618

UniProt: P34998

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity