CRHR1 Antikörper (AA 250-263)

Produktnummer ABIN190893

Produktdetails anti-CRHR1 Antikörper

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Bindungsspezifität: AA 250-263

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CRHR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: CRHR1 / CRF-R (aa 250 - 263)

Sequenz: KLYYDNEKCW FGKR

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte, Schaf

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence KLYYDNEKCWFGKR, from the internal region of the protein sequence according to NP_004373.2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Brain (Cortex). Recommended concentration: 5 μg/mL.

Western Blot: This antibody has been successfully used in WB on Mouse: Hunt AJ Jr et al, Brain Struct Funct. 2018 Jul,223(6):2685-2698. PMID: 29569009.

Peptide ELISA: antibody detection limit dilution 1:1000.

Kommentare:

Immunofluorescence: Expression of the protein seen in the cytoplasm and vesicles of MCF7 cells. Recommended concentration: 10μg/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-CRHR1 Antikörper (ABIN190893)

Hunt, Dasgupta, Rajamanickam, Jiang, Beierlein, Chan, Justice: "Paraventricular hypothalamic and amygdalar CRF neurons synapse in the external globus pallidus." in: Brain structure & function, Vol. 223, Issue 6, pp. 2685-2698, (2019) (PubMed).

Details zu CRHR1

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Andere Bezeichnung: CRHR1 (CRHR1 Produkte)

Synonyme: CRF-R antikoerper, CRF-R-1 antikoerper, CRF-R1 antikoerper, CRF1 antikoerper, CRFR-1 antikoerper, CRFR1 antikoerper, CRH-R-1 antikoerper, CRH-R1 antikoerper, CRH-R1h antikoerper, CRHR antikoerper, CRHR1L antikoerper, CRHR1f antikoerper, Crhr antikoerper, crhr1 antikoerper, crhr1-A antikoerper, CRHR1 antikoerper, CRHR1-IT1-CRHR1 antikoerper, MGC57346-CRHR1 antikoerper, corticotropin releasing hormone receptor 1 antikoerper, corticotropin releasing hormone receptor 1, gene 2 S homeolog antikoerper, corticotropin-releasing factor receptor 1 antikoerper, LINC02210-CRHR1 readthrough antikoerper, CRHR1 antikoerper, Crhr1 antikoerper, crhr1.2.S antikoerper, LOC610380 antikoerper, LOC100065598 antikoerper, LINC02210-CRHR1 antikoerper, crhr1 antikoerper

Hintergrund: CRHR1, CRF-R, corticotropin releasing hormone receptor 1 , CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f , corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor

Gen-ID: 1394, 12921, 58959

NCBI Accession: NP_004373

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity