NR1H2 Antikörper (N-Term)

Produktnummer ABIN374475

Produktdetails anti-NR1H2 Antikörper

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NR1H2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: SSPTTSSLDT PLPGC

Spezifität: This antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_009052.3

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/64000. Western blot: 1-3 μg/mL. Immunohistochemistry: 1-2 μg/mL. In paraffin embedded Human Spleen shows nucleolarstaining.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu NR1H2

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Andere Bezeichnung: NR1H2 (NR1H2 Produkte)

Synonyme: NR1H2 antikoerper, lxr-b antikoerper, lxrb antikoerper, ner antikoerper, ner-i antikoerper, rip15 antikoerper, unr antikoerper, DKFZp468A0622 antikoerper, AI194859 antikoerper, LXR antikoerper, LXRB antikoerper, LXRbeta antikoerper, NER1 antikoerper, OR-1 antikoerper, RIP15 antikoerper, UR antikoerper, Unr antikoerper, Unr2 antikoerper, LXR-b antikoerper, NER antikoerper, NER-I antikoerper, UNR antikoerper, nuclear receptor subfamily 1 group H member 2 antikoerper, nuclear receptor subfamily 1, group H, member 2 antikoerper, nuclear receptor subfamily 1 group H member 2 L homeolog antikoerper, NR1H2 antikoerper, nr1h2 antikoerper, Nr1h2 antikoerper, nr1h2.L antikoerper

Hintergrund: LXR beta is an orphan receptor which belongs to the nuclear hormone receptor family, NR1 subfamily. Ubiquitously expressed, it binds preferentially to double stranded oligonucleotide direct repeats having the consensus half site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Forms a heterodimer with RXR.Synonyms: LXRB, Liver X receptor beta, NER, Nuclear orphan receptor LXR-beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Oxysterols receptor LXR-beta, UNR, Ubiquitously-expressed nuclear receptor

Gen-ID: 7376

NCBI Accession: NP_009052

UniProt: P55055

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding