NR1H2 Antikörper (N-Term)

Produktnummer ABIN2780830

Produktdetails anti-NR1H2 Antikörper

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1H2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GNGPPQPGAP SSSPTVKEEG PEPWPGGPDP DVPGTDEASS ACSTDWVIPD

Homologie: Dog: 90%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NR1H2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 460 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NR1H2 Antikörper (ABIN2780830)

Bogan, Hennebold: "The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteum." in: Reproduction (Cambridge, England), Vol. 139, Issue 1, pp. 163-76, (2009) (PubMed).

Details zu NR1H2

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Andere Bezeichnung: NR1H2 (NR1H2 Produkte)

Synonyme: NR1H2 antikoerper, lxr-b antikoerper, lxrb antikoerper, ner antikoerper, ner-i antikoerper, rip15 antikoerper, unr antikoerper, DKFZp468A0622 antikoerper, AI194859 antikoerper, LXR antikoerper, LXRB antikoerper, LXRbeta antikoerper, NER1 antikoerper, OR-1 antikoerper, RIP15 antikoerper, UR antikoerper, Unr antikoerper, Unr2 antikoerper, LXR-b antikoerper, NER antikoerper, NER-I antikoerper, UNR antikoerper, nuclear receptor subfamily 1 group H member 2 antikoerper, nuclear receptor subfamily 1, group H, member 2 antikoerper, nuclear receptor subfamily 1 group H member 2 L homeolog antikoerper, NR1H2 antikoerper, nr1h2 antikoerper, Nr1h2 antikoerper, nr1h2.L antikoerper

Hintergrund: The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995).[supplied by OMIM].
Alias Symbols: LXR-b, LXRB, NER, NER-I, RIP15, UNR
Protein Interaction Partner: RXRG, MDFI, KDM1A, SUV39H1, ACVRL1, LAMC3, NCOR2, YY1, NPY, CDKN1A, PPARGC1B, PDCD4, PIAS1, USP7, PRKCA, SENP3, CORO2A, MPP1, COL4A5, CHD3, RMI1, CSAD, DUSP12, C14orf1, FAF1, SPRY2, HMGXB4, SORBS2, BAG6, VIM, UBE2D1, SMPD1, ROBO2, NCOR1, NRIP1, NCOA3, VDR
Protein Size: 460

Molekulargewicht: 51 kDa

Gen-ID: 7376

NCBI Accession: NM_007121, NP_009052

UniProt: Q68CY8

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding