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NR1H2 Produkte

(Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
The liver X receptors, LXRA (NR1H3\; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs\; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].

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Ausgewählte NR1H2 Kategorien

NR1H2 Antikörper

High quality antibodies with extensive validation data.

NR1H2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NR1H2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NR1H2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, ICC, IP
Validierungen
  • (7)
Kat. Nr. ABIN7444937
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN521265
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, FACS
Validierungen
  • (4)
Kat. Nr. ABIN185293
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NR1H2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969009
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN579470
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN454778
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NR1H2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312932
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7420831
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419373
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NR1H2 Produkten

Savic, Ramaker, Roberts, Dean, Burwell, Meadows, Cooper, Garabedian, Gertz, Myers: "Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation." in: Genome medicine, Vol. 8, Issue 1, pp. 74, (2016) (PubMed).

Rideout, Carrier, Wen, Raslawsky, Browne, Harding: "Complementary Cholesterol-Lowering Response of a Phytosterol/?-Lipoic Acid Combination in Obese Zucker Rats." in: Journal of dietary supplements, (2015) (PubMed).

Mohammadi, Oshaghi: "Effect of garlic on lipid profile and expression of LXR alpha in intestine and liver of hypercholesterolemic mice." in: Journal of diabetes and metabolic disorders, Vol. 13, Issue 1, pp. 20, (2014) (PubMed).

Pencheva, Buss, Posada, Merghoub, Tavazoie: "Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation." in: Cell, Vol. 156, Issue 5, pp. 986-1001, (2014) (PubMed).

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Yoon, Ju, Lee, Park, Lee, Shin, Holzapfel, Park, Do: "The probiotic Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum NR74 promote cholesterol efflux and suppress inflammation in THP-1 cells." in: Journal of the science of food and agriculture, Vol. 93, Issue 4, pp. 781-7, (2013) (PubMed).

Yoon, Ju, Kim, Park, Ji, Lee, Shin, Do, Holzapfel et al.: "Reduction in cholesterol absorption in Caco-2 cells through the down-regulation of Niemann-Pick C1-like 1 by the putative probiotic strains Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum ..." in: International journal of food sciences and nutrition, Vol. 64, Issue 1, pp. 44-52, (2013) (PubMed).

Guo, Zhang, Brockman, Hahn, Bernlohr, Chen: "Lipocalin 2 deficiency alters estradiol production and estrogen receptor signaling in female mice." in: Endocrinology, Vol. 153, Issue 3, pp. 1183-93, (2012) (PubMed).

Aye, Waddell, Mark, Keelan: "Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors." in: Placenta, Vol. 32, Issue 2, pp. 183-91, (2011) (PubMed).

Chen, Wang, Irwin, Yao, Liu, Brinton: "Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease." in: PLoS ONE, Vol. 6, Issue 8, pp. e24293, (2011) (PubMed).

Synonyme und alternative Namen zu NR1H2

nuclear receptor subfamily 1 group H member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 (nr1h2), nuclear receptor subfamily 1, group H, member 2 (Nr1h2), nuclear receptor subfamily 1, group H, member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 L homeolog (nr1h2.L), AI194859, DKFZp468A0622, LXR, lxr-b, LXR-b, lxrb, LXRB, LXRbeta, ner, NER, ner-i, NER-I, NER1, NR1H2, OR-1, rip15, RIP15, unr, Unr, UNR, Unr2, UR

Bezeichner auf Proteinebene für NR1H2

  • nuclear receptor subfamily 1, group H, member 2
  • LXR beta
  • liver X receptor beta
  • oxysterols receptor LXR-beta
  • retinoid X receptor-interacting protein No.15
  • ubiquitously-expressed nuclear receptor 2
  • UR
  • nuclear orphan receptor LXR-beta
  • orphan nuclear receptor OR-1
  • ubiquitous receptor
  • ubiquitously-expressed nuclear receptor
  • LX receptor beta
  • liver X nuclear receptor beta
  • nuclear receptor NER
  • steroid hormone-nuclear receptor NER
  • nuclear receptor subfamily 1 group H member 2
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