FOXA2 Antikörper (C-Term)

Produktnummer ABIN374335

Produktdetails anti-FOXA2 Antikörper

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FOXA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-GVYSRPIMNS S

Spezifität: This antibody detects FOXA2 at C-term. It is expected to recognise both reported isoforms.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Syntehtic peptide from the C-Terminus of the protein sequence according to NP_068556.2, NP_710141.1. Genename: FOXA2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 2000. Western blot: 0.5 μg/mL. Approx 60-65 kDa band observed in Human Liver lysate (predictedMW of 55 kDa according to NP_068556 and NP_710141).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Andere Bezeichnung: FOXA2 / HNF3B (FOXA2 Produkte)

Synonyme: hnf3b antikoerper, tcf3b antikoerper, hnf3beta antikoerper, hnf3-beta antikoerper, FOXA2 antikoerper, HNF3B antikoerper, TCF3B antikoerper, HNF-3B antikoerper, ax antikoerper, axl antikoerper, fkd1 antikoerper, ik:tdsubc_2g8 antikoerper, tdsubc_2g8 antikoerper, wu:fe05g04 antikoerper, xx:tdsubc_2g8 antikoerper, FoxA2-A antikoerper, FoxA2a antikoerper, xFD-3 antikoerper, xbeta-1 antikoerper, HNF-3b antikoerper, HNF3-beta antikoerper, HNF3beta antikoerper, Hnf-3b antikoerper, Hnf3b antikoerper, Tcf-3b antikoerper, Tcf3b antikoerper, HNF-3BETA antikoerper, forkhead box A2 antikoerper, forkhead box A2 L homeolog antikoerper, foxa2 antikoerper, FOXA2 antikoerper, foxa2.L antikoerper, Foxa2 antikoerper

Hintergrund: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.Synonyms: HNF-3-beta, HNF-3B, Hepatocyte nuclear factor 3-beta, TCF3B, Transcription factor 3B

Gen-ID: 3170

NCBI Accession: NP_068556

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process