KIF5B Antikörper (C-Term)

Produktnummer ABIN374232

Produktdetails anti-KIF5B Antikörper

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KIF5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-QPVAVRGGGG KQV

Spezifität: This antibody detects KIF5B at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Cow.
Species reactivity (tested):Human, Dog.

Aufreinigung: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_004512.1 Genename: KIF5B

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western blot: Approx 120 kDa band observed in Human Kidney lysates (calculated MW of110 kDa according to NP_004512.1). Recommended dilution: 0.2 - 1 μg/mL. Immunohistochemistry on paraffin sections: Human Kidney, shows perinuclear labelling ofsome glomerular cells and cytoplasmic staining of renal tubules. Recommended concentration: 1 - 2 μg/mL. In paraffin embedded Human Uterus shows strong staining of the epithelium on

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Andere Bezeichnung: KIF5B (KIF5B Produkte)

Synonyme: KINH antikoerper, KNS antikoerper, KNS1 antikoerper, UKHC antikoerper, Khc antikoerper, AL022807 antikoerper, Khcs antikoerper, Kns1 antikoerper, Ukhc antikoerper, khc antikoerper, KIF5A antikoerper, kinesin family member 5B antikoerper, kinesin heavy chain antikoerper, kinesin-1 antikoerper, kinesin-1 heavy chain antikoerper, kinesin family member 5B S homeolog antikoerper, KIF5B antikoerper, LOC411769 antikoerper, cgd6_2790 antikoerper, kin-1 antikoerper, Tb927.1.1350 antikoerper, LACBIDRAFT_305999 antikoerper, Khc antikoerper, LOC100538629 antikoerper, Kif5b antikoerper, kif5b.S antikoerper

Hintergrund: Kinesins are a superfamily of microtubule-based motor proteins involved in a variety of cellular processes including the transport of organelles in eukaryotic cells and cell division. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.Synonyms: Conventional kinesin heavy chain, KIF5B, KNS, KNS1, Kinesin-1 heavy chain, UKHC, Ubiquitous kinesin heavy chain

Gen-ID: 3799

NCBI Accession: NP_004512

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization