KIF5B Antikörper (AA 650-770)

Produktnummer ABIN7268136

Produktdetails anti-KIF5B Antikörper

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Bindungsspezifität: AA 650-770

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: KIF5B Rabbit pAb

Sequenz: LQNVEQKKRQ LEESVDALSE ELVQLRAQEK VHEMEKEHLN KVQTANEVKQ AVEQQIQSHR ETHQKQISSL RDEVEAKAKL ITDLQDQNQK MMLEQERLRV EHEKLKATDQ EKSRKLHELT V

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 650-770 of human KIF5B (NP_004512.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Andere Bezeichnung: KIF5B (KIF5B Produkte)

Synonyme: KINH antikoerper, KNS antikoerper, KNS1 antikoerper, UKHC antikoerper, Khc antikoerper, AL022807 antikoerper, Khcs antikoerper, Kns1 antikoerper, Ukhc antikoerper, khc antikoerper, KIF5A antikoerper, kinesin family member 5B antikoerper, kinesin heavy chain antikoerper, kinesin-1 antikoerper, kinesin-1 heavy chain antikoerper, kinesin family member 5B S homeolog antikoerper, KIF5B antikoerper, LOC411769 antikoerper, cgd6_2790 antikoerper, kin-1 antikoerper, Tb927.1.1350 antikoerper, LACBIDRAFT_305999 antikoerper, Khc antikoerper, LOC100538629 antikoerper, Kif5b antikoerper, kif5b.S antikoerper

Hintergrund: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs toward the immune synapse between effector NK lymphocytes and target cells.,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,KIF5B

Molekulargewicht: 109kDa

Gen-ID: 3799

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization