ARPC2 Antikörper (C-Term)

Produktnummer ABIN374215

Produktdetails anti-ARPC2 Antikörper

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ARPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-EMKTITGKTF SSR

Spezifität: This antibody detects ARPC2 / ARC34 at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog) and CowSpecies reactivity (tested):Human

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_005722.1, NP_690601.1. Genename: ARPC2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.1-0.5 μg/mL. Approx 33-34 kDa band observed in Hela and Human SkeletalMuscle lysates (predicted MW of 34 kDa according to NP_005722). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Spleen shows cytoplasmstaining in some splenocytes in and around a T-cell area.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ARPC2

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Andere Bezeichnung: ARPC2 / ARC34 (ARPC2 Produkte)

Synonyme: arc34 antikoerper, p34-arc antikoerper, pnas-139 antikoerper, pro2446 antikoerper, Arpc2 antikoerper, Arc-p34 antikoerper, 2210023N03Rik antikoerper, 34kDa antikoerper, p34-Arc antikoerper, fk84a07 antikoerper, wu:fa22f07 antikoerper, wu:fk84a07 antikoerper, zgc:77769 antikoerper, ARC34 antikoerper, PNAS-139 antikoerper, actin related protein 2/3 complex subunit 2 antikoerper, actin related protein 2/3 complex, subunit 2, 34kDa antikoerper, actin related protein 2/3 complex, subunit 2 antikoerper, actin related protein 2/3 complex subunit 2 S homeolog antikoerper, ARPC2 antikoerper, arpc2 antikoerper, Arpc2 antikoerper, arpc2.S antikoerper

Hintergrund: ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.Synonyms: Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, PRO2446, p34-ARC

Gen-ID: 10109

NCBI Accession: NP_005722

UniProt: O15144

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization