PTGDS Antikörper

Produktnummer ABIN363611

Produktdetails anti-PTGDS Antikörper

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Reacts with Prostaglandin D Synthase from human, mouse, rat, bovine, canine, feline, primate and rabbit

Aufreinigung: Antigen affinity purified

Immunogen: The epitope recognized by this antibody maps to region within residue 120-190 of human PTGDS

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 6 months

Details zu PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Andere Bezeichnung: Prostaglandin D Synthase (PTGDS) (PTGDS Produkte)

Synonyme: 6PGD antikoerper, GSTS antikoerper, GSTS1-1 antikoerper, PGD2 antikoerper, PGDS antikoerper, L-PGDS antikoerper, LPGDS antikoerper, PDS antikoerper, PGDS2 antikoerper, H-PGDS antikoerper, Ptgds2 antikoerper, 21kDa antikoerper, Ptgs3 antikoerper, PH2DISO antikoerper, phosphogluconate dehydrogenase antikoerper, hematopoietic prostaglandin D synthase antikoerper, prostaglandin D2 synthase antikoerper, prostaglandin D2 synthase (brain) antikoerper, prostaglandin D synthase antikoerper, prostaglandin D2 synthase 21kDa (brain) antikoerper, PGD antikoerper, HPGDS antikoerper, PTGDS antikoerper, Hpgds antikoerper, Ptgds antikoerper, LOC100009453 antikoerper

Hintergrund: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluidand recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.