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PTGDS Produkte

(Prostaglandin D2 Synthase (PTGDS))

Kategorien

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008].

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Ausgewählte PTGDS Kategorien

PTGDS Antikörper

High quality antibodies with extensive validation data.

PTGDS ELISA Kits

Reliable ELISA kits for a wide range of species.

PTGDS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PTGDS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN2783248
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN2783496
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7164874
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PTGDS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (4)
Kat. Nr. ABIN6574195
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969244
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969645
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PTGDS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3131393
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5710175
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316723
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PTGDS Produkten

Hamed, Laila-Al-Ayadhi, Osman, Elkhawad, Bjørklund, Qasem, Zayed, El-Ansary: "Determination of neuroinflammatory biomarkers in autistic and neurotypical Saudi children." in: Metabolic brain disease, Vol. 34, Issue 4, pp. 1049-1060, (2020) (PubMed).

Trimarco, Forese, Alfieri, Lucente, Brambilla, Dina, Pieragostino, Sacchetta, Urade, Boizet-Bonhoure, Martinelli Boneschi, Quattrini, Taveggia: "Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1682-92, (2014) (PubMed).

Huang, Huang, Lee, Yeh, Lin, Yu: "18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme." in: PLoS ONE, Vol. 9, Issue 8, pp. e104118, (2014) (PubMed).

Matsumoto, Eguchi, Oda, Yamane, Tarutani, Ozawa, Hayashi, Nakae, Horie, Urade: "Lipocalin-type prostaglandin D synthase is associated with coronary vasospasm and vasomotor reactivity in response to acetylcholine." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 75, Issue 4, pp. 897-904, (2011) (PubMed).

Takeda, Takahashi, Yoshizawa, Shibahara: "Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes." in: Journal of biochemistry, Vol. 148, Issue 2, pp. 139-48, (2010) (PubMed).

Huang, Lyu, Tseng, Chang, Hsu, Kuo, Chu, Wu, Ro, Huang, Chen: "Decreased intrathecal synthesis of prostaglandin D2 synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy." in: Journal of neuroimmunology, Vol. 206, Issue 1-2, pp. 100-5, (2009) (PubMed).

Le Mée, Hennebert, Ferrec, Wülfert, Morfin: "7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes." in: Steroids, Vol. 73, Issue 11, pp. 1148-59, (2008) (PubMed).

Lovell, Lynn, Xiong, Quinn, Kaye, Markesbery: "An aberrant protein complex in CSF as a biomarker of Alzheimer disease." in: Neurology, Vol. 70, Issue 23, pp. 2212-8, (2008) (PubMed).

Kanekiyo, Ban, Aritake, Huang, Qu, Okazaki, Mohri, Murayama, Ozono, Taniike, Goto, Urade: "Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 15, pp. 6412-7, (2007) (PubMed).

Synonyme und alternative Namen zu PTGDS

phosphogluconate dehydrogenase (PGD), hematopoietic prostaglandin D synthase (HPGDS), prostaglandin D2 synthase (PTGDS), hematopoietic prostaglandin D synthase (Hpgds), prostaglandin D2 synthase (brain) (Ptgds), prostaglandin D2 synthase (Ptgds), prostaglandin D synthase (LOC100009453), prostaglandin D2 synthase 21kDa (brain) (PTGDS), 6PGD, 21kDa, GSTS, GSTS1-1, H-PGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2, PH2DISO, Ptgds2, Ptgs3

Bezeichner auf Proteinebene für PTGDS

  • 6-phosphogluconate dehydrogenase, decarboxylating
  • GST class-sigma
  • glutathione S-transferase sigma
  • glutathione-dependent PGD synthase
  • glutathione-dependent PGD synthetase
  • glutathione-requiring prostaglandin D synthase
  • hematopoietic prostaglandin D2 synthase
  • prostaglandin-H2 D-isomerase
  • PGD2 synthase
  • beta-trace protein
  • cerebrin-28
  • glutathione-independent PGD synthase
  • glutathione-independent PGD synthetase
  • lipocalin-type prostaglandin D synthase
  • lipocalin-type prostaglandin-D synthase
  • prostaglandin D synthase
  • prostaglandin-D2 synthase
  • glutathione S-transferase
  • prostaglandin D2 synthase 2, hematopoietic
  • H-PGDS
  • prostaglandin-D synthase
  • prostaglandin D2 synthase (21 kDa, brain)
  • PGDS
  • PGDS2
  • Prostaglandin D synthase
  • prostaglandin D2 synthase 21kDa (brain)
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