PTK6 Produkte
(PTK6 Protein tyrosine Kinase 6 (PTK6))
Kategorien
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
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Ausgewählte PTK6 Kategorien
PTK6 Antikörper
High quality antibodies with extensive validation data.
PTK6 ELISA Kits
Reliable ELISA kits for a wide range of species.
PTK6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTK6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN519483
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN392105
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7263521
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PTK6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958992
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5519121
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380961
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTK6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5569664
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316783
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316782
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTK6 Produkten
: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).: "The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling." in: Marine drugs, Vol. 12, Issue 4, pp. 2282-304, (2014) (PubMed).
: "Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors." in: European journal of medicinal chemistry, Vol. 73, pp. 310-24, (2014) (PubMed).
: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).
: "Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models." in: PLoS ONE, Vol. 9, Issue 5, pp. e97622, (2014) (PubMed).
: "Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling." in: Organic & biomolecular chemistry, Vol. 12, Issue 28, pp. 5295-303, (2014) (PubMed).
: "Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo." in: Molecular oncology, Vol. 9, Issue 1, pp. 282-94, (2014) (PubMed).
: "Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma." in: Journal of translational medicine, Vol. 11, pp. 59, (2013) (PubMed).
: "A chemical and phosphoproteomic characterization of dasatinib action in lung cancer." in: Nature chemical biology, Vol. 6, Issue 4, pp. 291-9, (2010) (PubMed).
: "Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells." in: Oncogene, Vol. 22, Issue 27, pp. 4212-20, (2003) (PubMed).
Synonyme und alternative Namen zu PTK6
protein tyrosine kinase 6 (PTK6), PTK6 protein tyrosine kinase 6 (Ptk6), protein tyrosine kinase 6 (Ptk6), PTK6 protein tyrosine kinase 6b (ptk6b), BRK, Sik, tks, Tksk, zgc:153964Bezeichner auf Proteinebene für PTK6
- PTK6 protein tyrosine kinase 6
- breast tumor kinase
- protein-tyrosine kinase 6
- protein-tyrosine kinase BRK
- tyrosine-protein kinase BRK
- protein tyrosine kinase 6
- src-related intestinal kinase
- tyrosine kinase identified from skin
- protein-tyrosine kinase 6-like
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