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PTP4A3 Produkte

(Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq, Jul 2008].

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Ausgewählte PTP4A3 Kategorien

PTP4A3 Antikörper

High quality antibodies with extensive validation data.

PTP4A3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PTP4A3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PTP4A3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IP
Validierungen
  • (3)
Kat. Nr. ABIN7435550
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, ICC, IF
Validierungen
  • (3)
Kat. Nr. ABIN6264515
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN1682391
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PTP4A3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958954
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884249
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6384905
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PTP4A3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN7275479
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666667
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316805
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PTP4A3 Produkten

Gari, DeGala, Ray, Lucia, Lambert: "PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasion." in: Cancer letters, Vol. 380, Issue 2, pp. 505-12, (2016) (PubMed).

Gari, DeGala, Lucia, Lambert: "Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth." in: Oncogenesis, Vol. 5, Issue 8, pp. e255, (2016) (PubMed).

Ye, Al-Aidaroos, Park, Yuen, Zhang, Gupta, Lin, Shen, Zeng: "PRL-3 activates mTORC1 in Cancer Progression." in: Scientific reports, Vol. 5, pp. 17046, (2015) (PubMed).

Fromont, Godet, Peyret, Irani, Celhay, Rozet, Cathelineau, Cussenot: "8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy." in: Human pathology, Vol. 44, Issue 8, pp. 1617-23, (2013) (PubMed).

Fagerli, Holt, Holien, Vaatsveen, Zhan, Egeberg, Barlogie, Waage, Aarset, Dai, Shaughnessy, Sundan, Børset: "Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells." in: Blood, Vol. 111, Issue 2, pp. 806-15, (2008) (PubMed).

Kozlov, Cheng, Ziomek, Banville, Gehring, Ekiel: "Structural insights into molecular function of the metastasis-associated phosphatase PRL-3." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11882-9, (2004) (PubMed).

Kim, Song, Jee, Sheen, Lee, Lee, Ro, Cho, Lee, Yamazaki, Jeon, Cheong: "Structure of human PRL-3, the phosphatase associated with cancer metastasis." in: FEBS letters, Vol. 565, Issue 1-3, pp. 181-7, (2004) (PubMed).

Wu, Zeng, Zhang, Zhao, Sha, Ge, Zhang, Gao, Xu: "Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells." in: The American journal of pathology, Vol. 164, Issue 6, pp. 2039-54, (2004) (PubMed).

Kato, Semba, Miskad, Seo, Kasuga, Yokozaki: "High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 21, pp. 7318-28, (2004) (PubMed).

Bardelli, Saha, Sager, Romans, Xin, Markowitz, Lengauer, Velculescu, Kinzler, Vogelstein: "PRL-3 expression in metastatic cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 15, pp. 5607-15, (2003) (PubMed).

Synonyme und alternative Namen zu PTP4A3

protein tyrosine phosphatase type IVA, member 3 (PTP4A3), protein tyrosine phosphatase type IVA, member 3 (ptp4a3), protein tyrosine phosphatase type IVA, member 3 L homeolog (ptp4a3.L), protein tyrosine phosphatase 4a3 (Ptp4a3), protein tyrosine phosphatase type IVA, member 3 (Ptp4a3), AV088979, pPtp4a3, PRL-3, prl-3, Prl-3, PRL-R, PRL3, prl3, PTP4A3, ptpcaax3, wu:fc54b05, wu:fv52d11, zgc:77109

Bezeichner auf Proteinebene für PTP4A3

  • potentially prenylated protein tyrosine phosphatase
  • protein tyrosine phosphatase type IVA 3
  • protein-tyrosine phosphatase 4a3
  • protein-tyrosine phosphatase of regenerating liver 3
  • PRL-3
  • fc54b05
  • fv52d11
  • xPRL-3
  • protein tyrosine phosphatase type IVA, member 3
  • protein tyrosine phosphatase 4a3
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