PTPN21 Produkte
(Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008].
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Ausgewählte PTPN21 Kategorien
PTPN21 Antikörper
High quality antibodies with extensive validation data.
PTPN21 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPN21 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN392838
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7444973
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC
Validierungen
- (2)
Kat. Nr.
ABIN5014222
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PTPN21 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7419742
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7419433
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094803
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPN21 Produkten
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41124-32, (2001) (PubMed).
: "Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis." in: International journal of urology : official journal of the Japanese Urological Association, Vol. 6, Issue 11, pp. 572-7, (2000) (PubMed).
Synonyme und alternative Namen zu PTPN21
protein tyrosine phosphatase, non-receptor type 21 (PTPN21), protein tyrosine phosphatase, non-receptor type 21 (Ptpn21), Ptp2E, PTPD1, PTPRL10Bezeichner auf Proteinebene für PTPN21
- dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21)
- protein tyrosine phosphatase D1
- protein-tyrosine phosphatase D1
- tyrosine-protein phosphatase non-receptor type 21
- protein-tyrosine phosphatase PTP-RL10
- protein tyrosine phosphatase 2E
- protein-tyrosine phosphatase 2E
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