PTPN7 Produkte
(Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010].
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Ausgewählte PTPN7 Kategorien
PTPN7 Antikörper
High quality antibodies with extensive validation data.
PTPN7 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPN7 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN543957
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN1500502
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN7174120
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PTPN7 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228859
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTPN7 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124682
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316853
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316855
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPN7 Produkten
: "Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases." in: The Biochemical journal, Vol. 395, Issue 3, pp. 483-91, (2006) (PubMed).: "Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site." in: Journal of molecular biology, Vol. 354, Issue 1, pp. 150-63, (2005) (PubMed).
: "Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location." in: The Biochemical journal, Vol. 378, Issue Pt 2, pp. 335-42, (2004) (PubMed).
: "The protein tyrosine phosphatase HePTP regulates nuclear translocation of ERK2 and can modulate megakaryocytic differentiation of K562 cells." in: Leukemia, Vol. 17, Issue 2, pp. 366-78, (2003) (PubMed).
: "Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene." in: American journal of human genetics, Vol. 71, Issue 2, pp. 389-94, (2002) (PubMed).
: "Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome." in: Nature genetics, Vol. 29, Issue 4, pp. 465-8, (2001) (PubMed).
: "Subcellular localization of intracellular protein tyrosine phosphatases in T cells." in: European journal of immunology, Vol. 30, Issue 8, pp. 2412-21, (2000) (PubMed).
Synonyme und alternative Namen zu PTPN7
protein tyrosine phosphatase, non-receptor type 7 (PTPN7), protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), BPTP-4, C920001D21Rik, HEPTP, Heptp, LC-PTP, Lcptp, LPTP, PTPNIBezeichner auf Proteinebene für PTPN7
- dual specificity phosphatase 1
- hematopoietic protein-tyrosine phosphatase
- protein-tyrosine phosphatase LC-PTP
- protein-tyrosine phosphatase, nonreceptor-type, stress induced
- tyrosine-protein phosphatase non-receptor type 7
- protein-tyrosine phosphatase, non-receptor type 7
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