PTPN7 Antikörper (AA 22-51)

Produktnummer ABIN391869

Produktdetails anti-PTPN7 Antikörper

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Bindungsspezifität: AA 22-51

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7.

Klon: RB11327

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PTPN7

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Andere Bezeichnung: PTPN7 (PTPN7 Produkte)

Synonyme: BPTP-4 antikoerper, HEPTP antikoerper, LC-PTP antikoerper, LPTP antikoerper, PTPNI antikoerper, C920001D21Rik antikoerper, Heptp antikoerper, Lcptp antikoerper, protein tyrosine phosphatase, non-receptor type 7 antikoerper, PTPN7 antikoerper, Ptpn7 antikoerper

Hintergrund: PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.

Molekulargewicht: 40529

Gen-ID: 5778

NCBI Accession: NP_542155

UniProt: P35236