PTP4A3 Protein (AA 1-173) (His tag)

Produktnummer ABIN666667

Produktdetails

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-173

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PTP4A3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PRL-3, 1-173 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 2 mM EDTA, 1 mM DTT, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Andere Bezeichnung: PRL-3 (PTP4A3 Produkte)

Synonyme: PRL-3 Protein, PRL-R Protein, PRL3 Protein, wu:fc54b05 Protein, wu:fv52d11 Protein, zgc:77109 Protein, prl-3 Protein, prl3 Protein, ptpcaax3 Protein, PTP4A3 Protein, AV088979 Protein, Prl-3 Protein, pPtp4a3 Protein, protein tyrosine phosphatase type IVA, member 3 Protein, protein tyrosine phosphatase type IVA, member 3 L homeolog Protein, protein tyrosine phosphatase 4a3 Protein, PTP4A3 Protein, ptp4a3 Protein, ptp4a3.L Protein, Ptp4a3 Protein

Hintergrund: Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. Recombinant human PRL-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PTP4A3, PRL3, Protein tyrosine phosphatase type IVA 3 Potentially prenylated protein tyrosine phosphatase, PRL 3, PRL R, PRLR, Protein tyrosine phosphatase 4a3, PTP 4A3, Protein Tyrosine Phosphatase Type IVA Member 3. NCBI no.: NP_116000

Molekulargewicht: 21.6 kDa (193aa), confirmed by MALDI-TOF.