PTGDS Antikörper (N-Term)

Produktnummer ABIN2783248

Der Kaninchen Polyklonal anti-PTGDS Antikörper wird verwendet zum Nachweis von PTGDS in Proben von Human, Maus, Ratte, Hund, Pferd, Kaninchen und Meerschweinchen. Er wurde validiert für WB und IHC.

Kurzübersicht für PTGDS Antikörper (N-Term) (ABIN2783248)

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PTGDS Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PTGDS Antibody - N-terminal region

Sequenz: MATHHTLWMG LALLGVLGDL QAAPEAQVSV QPNFQQDKFL GRWFSAGLAS

Homologie: Dog: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 80%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTGDS. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTGDS

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48154-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Andere Bezeichnung: PTGDS

Hintergrund:

Background Information: PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Prostaglandin D2 synthase 21 kDa (brain)

Alternative Symbols: PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS

Protein Name: Prostaglandin-H2 D-isomerase

Molekulargewicht: 21 kDa

Gen-ID: 5730

NCBI Accession: NP_000945

UniProt: P41222