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CDKN1B Antikörper (pThr198)
CDKN1B
Reaktivität: Human
EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-CDKN1B Antikörper
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Target
Alle CDKN1B Antikörper anzeigen
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Bindungsspezifität
Alle Epitope für CDKN1B Antikörper
pThr198
Reaktivität
Alle Reaktivitäten für CDKN1B Antikörper
Human
Wirt
Alle Wirte für CDKN1B Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CDKN1B Antikörper
Polyklonal
Konjugat
Alle Konjugate für CDKN1B Antikörper
Dieser CDKN1B Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CDKN1B Antikörper
Enzyme Immunoassay (EIA)
Spezifität
This antibody detects p27Kip1 pThr198.
Aufreinigung
Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T198 of human 27Kip1.
Isotyp
Ig Fraction
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Details zu CDKN1B
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Target
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Andere Bezeichnung
CDKN1B / KIP1 (CDKN1B Produkte )
Synonyme
CDKN4 antikoerper, KIP1 antikoerper, MEN1B antikoerper, MEN4 antikoerper, P27KIP1 antikoerper, cdkn1b antikoerper, sb:cb611 antikoerper, wu:fb63g10 antikoerper, wu:fb64g10 antikoerper, wu:fe18e03 antikoerper, CDKN1B antikoerper, Kip1 antikoerper, p27 antikoerper, FAM14D antikoerper, ISG12 antikoerper, ISG12A antikoerper, P27 antikoerper, Cdki1b antikoerper, AA408329 antikoerper, AI843786 antikoerper, p27Kip1 antikoerper, cdkn1bl antikoerper, cyclin dependent kinase inhibitor 1B antikoerper, cyclin-dependent kinase inhibitor 1Bb antikoerper, interferon alpha inducible protein 27 antikoerper, cyclin-dependent kinase inhibitor 1B antikoerper, cyclin-dependent kinase inhibitor 1Ba antikoerper, CDKN1B antikoerper, cdkn1bb antikoerper, IFI27 antikoerper, Cdkn1b antikoerper, cdkn1ba antikoerper
Hintergrund
P27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1
Molekulargewicht
22073 Da
Gen-ID
1027, 9606
UniProt
P46527
Pathways
Zellzyklus , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagie
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