TRPC4 Antikörper (4th Cytoplasmic Loop)

Produktnummer ABIN351140

Produktdetails anti-TRPC4 Antikörper

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Bindungsspezifität: 4th Cytoplasmic Loop

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for TRPC4.

Immunogen: A synthetic peptide from the 4th cytoplasmic loop of rat TRPC4 conjugated to an immunogenic carrier protein was used as the antigen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: A concentration of 10-50 µg/ml is recommended.
The optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu TRPC4

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Andere Bezeichnung: TRPC4 (TRPC4 Produkte)

Synonyme: TRPC5 antikoerper, TRPC4 antikoerper, HTRP-4 antikoerper, HTRP4 antikoerper, TRP4 antikoerper, CCE1 antikoerper, STRPC4 antikoerper, Trp4 antikoerper, Trrp4 antikoerper, transient receptor potential cation channel subfamily C member 4 antikoerper, short transient receptor potential channel 4 antikoerper, transient receptor potential cation channel, subfamily C, member 4 antikoerper, TRPC4 antikoerper, LOC100538928 antikoerper, trpc4 antikoerper, Trpc4 antikoerper

Hintergrund: Function: Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.
Subunit: Isoform alpha but not isoform beta associates with inositol-1,4,5-triphosphate receptor (ITPR). Interacts with NHERF. PROBABLE
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Short transient receptor potential channel 4, Trp4, Capacitative calcium entry channel 1, CCE1. GENE NAME: Trpc4.