TRPC4 Produkte
(Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))
Kategorien
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
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Ausgewählte TRPC4 Kategorien
TRPC4 Antikörper
High quality antibodies with extensive validation data.
TRPC4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TRPC4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC
Validierungen
- (17)
Kat. Nr.
ABIN571659
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN2776213
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN570934
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene TRPC4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6208207
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TRPC4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3130418
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3074900
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3074899
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TRPC4 Produkten
: "Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease." in: Inflammatory bowel diseases, Vol. 21, Issue 3, pp. 496-506, (2015) (PubMed).: "Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells." in: Biochimica et biophysica acta, Vol. 1853, Issue 2, pp. 377-87, (2015) (PubMed).
: "Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 10, pp. 3653-67, (2014) (PubMed).
: "Increased expression of TRPC4 channels associated with erectile dysfunction in diabetes." in: Andrology, Vol. 2, Issue 4, pp. 550-8, (2014) (PubMed).
: "Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32941-51, (2013) (PubMed).
: "Selective G?i subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17029-39, (2012) (PubMed).
: "Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells." in: American journal of physiology. Cell physiology, Vol. 303, Issue 6, pp. C635-44, (2012) (PubMed).
: "Mass spectrometric analysis of novel phosphorylation sites in the TRPC4? channel." in: Rapid communications in mass spectrometry : RCM, Vol. 26, Issue 17, pp. 1965-70, (2012) (PubMed).
: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).
: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).
Synonyme und alternative Namen zu TRPC4
transient receptor potential cation channel subfamily C member 4 (TRPC4), short transient receptor potential channel 4 (LOC100538928), transient receptor potential cation channel subfamily C member 4 (trpc4), transient receptor potential cation channel, subfamily C, member 4 (Trpc4), transient receptor potential cation channel subfamily C member 4 (Trpc4), CCE1, HTRP-4, HTRP4, STRPC4, TRP4, Trp4, TRPC4, TRPC5, Trrp4Bezeichner auf Proteinebene für TRPC4
- transient receptor potential 4
- transient receptor potential cation channel, subfamily C, member 5
- transient receptor potential cation channel, subfamily C, member 4
- short transient receptor potential channel 4-like
- short transient receptor potential channel 4
- trp-related protein 4
- capacitative calcium entry channel Trp4
- putative capacitative calcium entry channel
- receptor-activated cation channel TRP4
- transient receptor protein 4
- CCE1
- capacitative calcium entry channel 1
- transient receptor potential channel 4
- transient receptor potential protein 4
- transient receptor potential cation channel TRPC4 middle region 2
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