TRP63 Produkte
(Transformation Related Protein 63 (TRP63))
Kategorien
This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms.[provided by RefSeq, Dec 2009].
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Ausgewählte TRP63 Kategorien
TRP63 Antikörper
High quality antibodies with extensive validation data.
Empfohlene TRP63 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
Kat. Nr.
ABIN1019670
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN2778222
Menge
100 μL
Datenblatt
Datenblatt
Synonyme und alternative Namen zu TRP63
transformation related protein 63 (Trp63), AI462811, Ket, P51/P63, P63, P73l, Tp63, Trp53rp1Bezeichner auf Proteinebene für TRP63
- transformation-related protein 63
- tumor protein 63
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