ERN2 Antikörper (AA 491-505)

Produktnummer ABIN343042

Produktdetails anti-ERN2 Antikörper

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Bindungsspezifität: AA 491-505

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ERN2 Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Human ERN2.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (93%) Marmoset (87%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-QKRLQSPSKQAQPLD from an internal region of human ERN2 (NP_150296.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey (93%), Marmoset (87%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:4000)

Usage: Peptide ELISA: antibody detection limit dilution 1:4000. Western Blot: Preliminary experiments gave an approx 37kD band in Human Duodenum, Pancreas and Placenta lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 107kD according to NP_150296.3. The 37kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Andere Bezeichnung: ERN2 (ERN2 Produkte)

Synonyme: Ire1beta antikoerper, ire1b antikoerper, Ern1 antikoerper, Ire1 antikoerper, Ire1b antikoerper, IRE1-BETA antikoerper, IRE1b antikoerper, endoplasmic reticulum to nucleus signaling 2 antikoerper, endoplasmic reticulum (ER) to nucleus signalling 2 antikoerper, ERN2 antikoerper, ern2 antikoerper, Ern2 antikoerper

Hintergrund: Name/Gene ID: ERN2
Subfamily: IRE
Family: Protein Kinase

Synonyms: ERN2, ER to nucleus signalling 2, HIRE2p, Inositol-requiring protein 2, IRE1-BETA, Inositol-requiring 1 beta, IRE1 beta, IRE2, IRE1b

Gen-ID: 10595

NCBI Accession: NP_150296

UniProt: Q76MJ5