ERN2 Antikörper
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- Target Alle ERN2 Antikörper anzeigen
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERN2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthetic peptide of human ERN2
- Isotyp
- IgG
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anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) (AA 39-72), (N-Term) antibody
ERN2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB8519 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) (AA 841-890) antibodyERN2 Reaktivität: Human, Maus ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
- Andere Bezeichnung
- ERN2 (ERN2 Produkte)
- Synonyme
- Ire1beta antikoerper, ire1b antikoerper, Ern1 antikoerper, Ire1 antikoerper, Ire1b antikoerper, IRE1-BETA antikoerper, IRE1b antikoerper, endoplasmic reticulum to nucleus signaling 2 antikoerper, endoplasmic reticulum (ER) to nucleus signalling 2 antikoerper, ERN2 antikoerper, ern2 antikoerper, Ern2 antikoerper
- Hintergrund
- The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein). IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.
- NCBI Accession
- NP_150296
- UniProt
- Q76MJ5
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