TUBGCP4 Antikörper

Produktnummer ABIN317908

Produktdetails anti-TUBGCP4 Antikörper

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBGCP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: GCP4 antibody detects endogenous levels of GCP4 protein.(region surrounding Leu225)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TUBGCP4

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Andere Bezeichnung: TUBGCP4 (TUBGCP4 Produkte)

Synonyme: RGD1306924 antikoerper, 76p antikoerper, MGC81229 antikoerper, zgc:194561 antikoerper, zgc:194580 antikoerper, DKFZp459O2210 antikoerper, 76P antikoerper, GCP-4 antikoerper, GCP4 antikoerper, h76p antikoerper, hGCP4 antikoerper, hGrip76 antikoerper, 4932441P04Rik antikoerper, D2Ertd435e antikoerper, tubulin, gamma complex associated protein 4 antikoerper, tubulin gamma complex associated protein 4 antikoerper, tubulin gamma complex associated protein 4 L homeolog antikoerper, Tubgcp4 antikoerper, TUBGCP4 antikoerper, tubgcp4.L antikoerper, tubgcp4 antikoerper

Hintergrund: The γ-Tubulin complex is composed of γ Tubulin and the γ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. γ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubulin complex. GCP4 (γ-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the γ-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.Synonyms: 76P, GCP-4, GCP4, Gamma-ring complex protein 76 kDa, Gamma-tubulin complex component 4, Grip76

Molekulargewicht: approx. 76 kDa

Gen-ID: 27229

NCBI Accession: NP_055259

UniProt: Q9UGJ1

Pathways: M Phase