PPP2R5D Antikörper (Catalytic Subunit)

Produktnummer ABIN306653

Produktdetails anti-PPP2R5D Antikörper

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Bindungsspezifität: Catalytic Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta,A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30 % of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a γ-phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 79.3, 16.9 and 3.8 % respectively of the phosphoproteome, at least in mammals. In contrast, protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes based on sequence, structure and catalytic function. The largest class of PPs is the phosphoprotein phosphatase (PPP) family comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg²- or Mn²-dependent (PPM) family, composed primarily of PP2C.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: The immunogen used to generate the purified antibody was a peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-IlePro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH. This peptide antibody corresponds to C -terminal peptide of PPV catalytic subunit having a MW of 33kDa.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Applications: Immunoblotting 1-10 μg/mL and 10-20 μg/mL for Immunoprecipitation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Andere Bezeichnung: Protein Phosphatase 2 A/B delta (PPP2R5D Produkte)

Synonyme: B56D antikoerper, B'delta antikoerper, TEG-271 antikoerper, Tex271 antikoerper, zgc:73160 antikoerper, zgc:77529 antikoerper, ppp2r5d antikoerper, MDS026 antikoerper, protein phosphatase 2 regulatory subunit B'delta antikoerper, protein phosphatase 2, regulatory subunit B', delta antikoerper, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antikoerper, protein phosphatase 2 regulatory subunit Bdelta antikoerper, PPP2R5D antikoerper, Ppp2r5d antikoerper, ppp2r5d antikoerper, LOC100176996 antikoerper, PPP2R2D antikoerper

Pathways: PI3K-Akt Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades