NLRC4 Antikörper (C-Term)

Produktnummer ABIN3043570

Produktdetails anti-NLRC4 Antikörper

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Bindungsspezifität: AA 838-874, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: KILAQNLHNL VKLSILDLSE NYLEKDGNEA LHELIDR

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: NLR family, CARD domain containing 4
Protein Name: NLR family CARD domain-containing protein 4

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CARD12 (838-874aa KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Andere Bezeichnung: NLRC4 (NLRC4 Produkte)

Synonyme: CARD12 antikoerper, CLAN antikoerper, CLAN1 antikoerper, CLANA antikoerper, CLANB antikoerper, CLANC antikoerper, CLAND antikoerper, CLR2.1 antikoerper, IPAF antikoerper, 9530011P19Rik antikoerper, Card12 antikoerper, NLR family CARD domain containing 4 antikoerper, NLR family, CARD domain containing 4 antikoerper, NLRC4 antikoerper, Nlrc4 antikoerper

Hintergrund: NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

Synonyms: and NACHT-containing protein antibody|CARD 12 antibody|CARD antibody|CARD LRR and NACHT containing protein 1 antibody|CARD LRR and NACHT containing protein antibody|CARD12 antibody|Caspase recruitment domain containing protein 12 antibody|Caspase recruitment domain family member 12 antibody|Caspase recruitment domain-containing protein 12 antibody|CLAN 1 antibody|CLAN A antibody|CLAN antibody|CLAN B antibody|CLAN C antibody|CLAN D antibody|Clan protein antibody|CLAN1 antibody|CLANA antibody|CLANB antibody|CLANC antibody| CLAND antibody|CLR 2.1 antibody|CLR2.1 antibody|ICE protease activating factor antibody|Ice protease-activating factor antibody|IPAF antibody|LRR antibody|NLR family CARD domain containing 4 antibody|NLR family CARD domain-containing protein 4 antibody|NLRC 4 antibody|NLRC4 antibody|NLRC4_HUMAN antibody|NOD like receptor C4 antibody|Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody|UNQ6189/PRO20215 antibody

Gen-ID: 58484

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome