IL2RG Antikörper (Middle Region)

Produktnummer ABIN3043145

Produktdetails anti-IL2RG Antikörper

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Bindungsspezifität: AA 88-102, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2RG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Cytokine receptor common subunit gamma(IL2RG) detection. Tested with WB in Human.

Sequenz: HYWYKNSDND KVQKC

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Cytokine receptor common subunit gamma(IL2RG) detection. Tested with WB in Human.
Gene Name: interleukin 2 receptor, gamma
Protein Name: Cytokine receptor common subunit gamma

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma(88-102aa HYWYKNSDNDKVQKC).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: IL2RG (IL2RG Produkte)

Synonyme: Ab2-183 antikoerper, Cd132 antikoerper, CD132 antikoerper, CIDX antikoerper, IL-2RG antikoerper, IMD4 antikoerper, P64 antikoerper, SCIDX antikoerper, SCIDX1 antikoerper, [g]c antikoerper, gamma(c) antikoerper, gc antikoerper, interleukin 2 receptor subunit gamma antikoerper, interleukin 2 receptor subunit gamma L homeolog antikoerper, interleukin 2 receptor, gamma chain antikoerper, IL2RG antikoerper, il2rg.L antikoerper, Il2rg antikoerper

Hintergrund: IL2RG(INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte(white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Synonyms: CD132 antibody|common cytokine receptor gamma chain antibody|Cytokine receptor common subunit gamma antibody|Gamma C antibody|gamma(c) antibody|gammaC antibody|IL-2 receptor subunit gamma antibody|IL-2R gamma chain antibody|IL-2R subunit gamma antibody|IL-2RG antibody|Il2rg antibody|IL2RG_HUMAN antibody|IMD4 antibody|interleukin 2 receptor, gamma antibody|Interleukin-2 receptor subunit gamma antibody|p64 antibody|SCIDX antibody|SCIDX1 antibody

UniProt: P31785

Pathways: JAK-STAT Signalweg, Growth Factor Binding