IL2RG Antikörper

Produktnummer ABIN6579821

Der Ratte Monoklonal anti-IL2RG Antikörper (Klon TUGh4) (ABIN6579821) detektiert spezifisch IL2RG in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Hund.

Kurzübersicht für IL2RG Antikörper (ABIN6579821)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Human, Hund

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2RG Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: TUGh4

Produktdetails anti-IL2RG Antikörper

Verwendungszweck: Anti-Hu CD132 Purified

Kreuzreaktivität (Details): Human, Canine (Dog)

Produktmerkmale: The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

Aufreinigung: Purified by protein-G affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human CD132-transfected cell line

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: CD132

Hintergrund: Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

Gen-ID: 3561

UniProt: P31785

Pathways: JAK-STAT Signalweg, Growth Factor Binding