IL5RA Antikörper (N-Term)

Produktnummer ABIN3043143

Produktdetails anti-IL5RA Antikörper

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Bindungsspezifität: AA 53-68, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL5RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Interleukin-5 receptor subunit alpha(IL5RA) detection. Tested with WB in Human.

Sequenz: NPDQEQRNVN LEYQVK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Interleukin-5 receptor subunit alpha(IL5RA) detection. Tested with WB in Human.
Gene Name: interleukin 5 receptor, alpha
Protein Name: Interleukin-5 receptor subunit alpha(IL-5 receptor subunit alpha/IL-5R subunit alpha/IL-5R-alpha/IL-5RA)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IL5RA(53-68aa NPDQEQRNVNLEYQVK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Andere Bezeichnung: IL5RA (IL5RA Produkte)

Synonyme: MGC86517 antikoerper, IL5RA antikoerper, il5r antikoerper, cdw125 antikoerper, hsil5r3 antikoerper, gpIL-5ra antikoerper, CD125 antikoerper, CDw125 antikoerper, HSIL5R3 antikoerper, IL5R antikoerper, Il5r antikoerper, interleukin 5 receptor subunit alpha L homeolog antikoerper, interleukin 5 receptor subunit alpha antikoerper, interleukin 5 receptor, alpha antikoerper, il5ra.L antikoerper, IL5RA antikoerper, il5ra antikoerper, Il5ra antikoerper

Hintergrund: IL5RA(INTERLEUKIN 5 RECEPTOR, ALPHA), also known as CD125, is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization. And its Cytogenetic location is 3p26.2. Within this 15-residue stretch of IL5RA, the C-terminal phenylalanine is critical. The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5.

Synonyms: CD125 antibody|CD125 antigen antibody|CDw125 antibody|HSIL5R3 antibody|IL-5 receptor subunit alpha antibody|IL-5R subunit alpha antibody|IL-5R-alpha antibody|IL-5RA antibody|IL5R antibody|IL5RA antibody|IL5RA_HUMAN antibody|Interleukin 5 Receptor alpha antibody|Interleukin 5 Receptor alpha chain antibody|Interleukin 5 receptor alpha subunit antibody|Interleukin 5 receptor subunit alpha antibody|Interleukin 5 receptor type 3 antibody|Interleukin-5 receptor subunit alpha antibody|MGC26560 antibody

UniProt: Q01344

Pathways: JAK-STAT Signalweg