IL5RA Antikörper (C-Term)

Produktnummer ABIN1537258

Produktdetails anti-IL5RA Antikörper

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Bindungsspezifität: AA 391-420, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL5RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.

Klon: RB40195

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IL5RA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Andere Bezeichnung: IL5RA (IL5RA Produkte)

Synonyme: MGC86517 antikoerper, IL5RA antikoerper, il5r antikoerper, cdw125 antikoerper, hsil5r3 antikoerper, gpIL-5ra antikoerper, CD125 antikoerper, CDw125 antikoerper, HSIL5R3 antikoerper, IL5R antikoerper, Il5r antikoerper, interleukin 5 receptor subunit alpha L homeolog antikoerper, interleukin 5 receptor subunit alpha antikoerper, interleukin 5 receptor, alpha antikoerper, il5ra.L antikoerper, IL5RA antikoerper, il5ra antikoerper, Il5ra antikoerper

Hintergrund: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Molekulargewicht: 47685

Gen-ID: 3568

NCBI Accession: NP_000555, NP_001230028, NP_783851, NP_783852, NP_783853, NP_783854, NP_783855

UniProt: Q01344

Pathways: JAK-STAT Signalweg