IRAK3 Antikörper (C-Term)

Produktnummer ABIN3042834

Produktdetails anti-IRAK3 Antikörper

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Bindungsspezifität: AA 543-562, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 3(IRAK3) detection. Tested with WB in Human.

Sequenz: WFPKYIVPSQ DLRPYKVNID

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 3(IRAK3) detection. Tested with WB in Human.
Gene Name: interleukin-1 receptor-associated kinase 3
Protein Name: Interleukin-1 receptor-associated kinase 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IRAKM(543-562aa WFPKYIVPSQDLRPYKVNID).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Andere Bezeichnung: IRAK3 (IRAK3 Produkte)

Synonyme: IRAK3 antikoerper, si:dkey-150i15.2 antikoerper, ASRT5 antikoerper, IRAKM antikoerper, IrakM antikoerper, 4833428C18Rik antikoerper, AI563835 antikoerper, IRAK-M antikoerper, interleukin 1 receptor associated kinase 3 antikoerper, interleukin-1 receptor-associated kinase 3 antikoerper, IRAK3 antikoerper, irak3 antikoerper, Irak3 antikoerper

Hintergrund: Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.

Synonyms: ASRT5 antibody|IL 1 receptor associated kinase M antibody|IL-1 receptor-associated kinase M antibody|IL1 receptor associated kinase M antibody|Interleukin 1 receptor associated kinase 3 antibody|Interleukin 1 receptor associated kinase M antibody|Interleukin-1 receptor-associated kinase 3 antibody|IRAK 3 antibody|IRAK M antibody|IRAK-3 antibody|IRAK-M antibody|IRAK3 antibody|IRAK3_HUMAN antibody

UniProt: Q9Y616

Pathways: TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades