PLA2G4A Antikörper (C-Term)

Produktnummer ABIN3032229

Produktdetails anti-PLA2G4A Antikörper

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Phospholipase A2 (PNQAFKRLHDLMHFN) was used as the immunogen for this CPLA2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CPLA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CPLA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PLA2G4A

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Andere Bezeichnung: CPLA2 (PLA2G4A Produkte)

Synonyme: PLA2G4 antikoerper, cPLA2-alpha antikoerper, Pla2c antikoerper, Pla2g4 antikoerper, cPLA2 antikoerper, pla2g4 antikoerper, CPLA2 antikoerper, PLA2G4A antikoerper, PLA2 antikoerper, PLA2G1B antikoerper, cPLA2alpha antikoerper, pla2g4a antikoerper, si:dkey-97o5.1 antikoerper, phospholipase A2 group IVA antikoerper, phospholipase A2 group IVA L homeolog antikoerper, phospholipase A2, group IVA (cytosolic, calcium-dependent) antikoerper, phospholipase A2, group IVAb (cytosolic, calcium-dependent) antikoerper, PLA2G4A antikoerper, Pla2g4a antikoerper, pla2g4a.L antikoerper, pla2g4ab antikoerper

Hintergrund: Cytosolic Phospholipase A2, Group IVA is an enzyme that in humans is encoded by the PLA2G4A gene. Tay et al.(1995) mapped the gene to rat chromosome 13 by PCR-based intercross genotyping and to human 1q25 by fluorescence in situ hybridization. By site-directed mutagenesis and biochemical analysis of the recombinant protein, Sharp et al.(1994) determined that ser228 participates in the catalytic mechanism of cPLA2 and that both the phospholipase A2 and the lysophospholipase activities are catalyzed by the same active site residue(s). PLA2G4A, the cytosolic phospholipase A2, appears to subserve transmembrane signaling responses to extracellular ligands(Skorecki, 1995).

UniProt: P47712

Pathways: Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling