HSP27 Antikörper (Middle Region)

Produktnummer ABIN3031144

Produktdetails anti-HSP27 Antikörper

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human HSP27 (KHEERQDEHGYISRCFTR) was used as the immunogen for this HSPB1 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the HSPB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the HSPB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu HSP27

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Andere Bezeichnung: HSPB1 (HSPB1 Produkte)

Synonyme: CMT2F antikoerper, HMN2B antikoerper, HS.76067 antikoerper, HSP27 antikoerper, HSP28 antikoerper, Hsp25 antikoerper, SRP27 antikoerper, 27kDa antikoerper, Hsp27 antikoerper, cb153 antikoerper, cb660 antikoerper, hsp1 antikoerper, hsp25 antikoerper, hsp27 antikoerper, id:ibd2821 antikoerper, sb:cb660 antikoerper, zgc:103437 antikoerper, HSPB1 antikoerper, cmt2f antikoerper, hs.76067 antikoerper, hsp28 antikoerper, heat shock protein family B (small) member 1 antikoerper, heat shock protein 1 antikoerper, heat shock protein, alpha-crystallin-related, 1 antikoerper, heat shock protein family B (small) member 1 L homeolog antikoerper, HSPB1 antikoerper, Hspb1 antikoerper, hspb1 antikoerper, hspb1.L antikoerper

Hintergrund: HSPB1 (Heat shock 27 kDa protein 1) is a protein that in humans is encoded by the HSPB1 gene. Stock et al.(2003) used FISH to map the HSP27 gene to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

UniProt: P04792

Pathways: MAPK Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling