COL3A1 Antikörper (C-Term)

Produktnummer ABIN3030551

Produktdetails anti-COL3A1 Antikörper

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL3A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: C-terminal amino acids VGAAAIAGIGGEKAGGFAPYYG were used as the immunogen for this Collagen III antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Collagen III antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Collagen III antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu COL3A1

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Andere Bezeichnung: Collagen III / COL3A1 (COL3A1 Produkte)

Synonyme: EDS4A antikoerper, AW550625 antikoerper, Col3a-1 antikoerper, MMS10-W antikoerper, Ms10w antikoerper, mKIAA4231 antikoerper, col3a1 antikoerper, collagen type III alpha 1 chain antikoerper, collagen, type III, alpha 1 antikoerper, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antikoerper, COL3A1 antikoerper, Col3a1 antikoerper, col3a1 antikoerper, col3a1.S antikoerper

Hintergrund: COL3A1, also called EDS4A or Collagen alpha-1(III), is a protein that in humans is encoded by the COL3A1 gene, it is mapped to 2q32.2. COL3A1 chain is a fibrillar-forming collagen comprising 3 alpha-1(III) chains and is expressed in early embryos and throughout embryogenesis. In adult, COL3A1 is a major component of the extracellular matrix in a variety of internal organs and skin. COL3A1 is also a fibrous scleroprotein in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. It is involved in regulation of cortical development, and it Is the major ligand of GPR56 in the developing brain.COL3A1 binding to GPR56 can inhibit neuronal migration and activate the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12

Gen-ID: 1281

Pathways: Autophagie, Growth Factor Binding