CFTR Antikörper

Produktnummer ABIN3024585

Produktdetails anti-CFTR Antikörper

Target: CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CFTR Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Human recombinant protein was used as the immunogen for this CFTR antibody.

Klon: CFTR1-1

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.

1. Staining of FFPE tissue is enhanced by boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9 for 10-20 min followed by cooling at RT for 20 min.\. Immunofluorescence: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CFTR

Target: CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))

Andere Bezeichnung: CFTR (CFTR Produkte)

Synonyme: ABC35 antikoerper, ABCC7 antikoerper, CF antikoerper, CFTR/MRP antikoerper, MRP7 antikoerper, TNR-CFTR antikoerper, dJ760C5.1 antikoerper, CFTR antikoerper, AW495489 antikoerper, Abcc7 antikoerper, RGD1561193 antikoerper, abc35 antikoerper, abcc7 antikoerper, cftr/mrp antikoerper, mrp7 antikoerper, tnr-cftr antikoerper, xcftr antikoerper, si:dkey-270i2.2 antikoerper, cystic fibrosis transmembrane conductance regulator antikoerper, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antikoerper, CFTR antikoerper, cftr-A antikoerper, Cftr antikoerper, cftr antikoerper

Hintergrund: Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Gen-ID: 1080