ABCG8 Antikörper (AA 1-320)

Produktnummer ABIN3022643

Produktdetails anti-ABCG8 Antikörper

Target: ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))

Bindungsspezifität: AA 1-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCG8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MAGKAAEERG LPKGATPQDT SGLQDRLFSS ESDNSLYFTY SGQPNTLEVR DLNYQVDLAS QVPWFEQLAQ FKMPWTSPSC QNSCELGIQN LSFKVRSGQM LAIIGSSGCG RASLLDVITG RGHGGKIKSG QIWINGQPSS PQLVRKCVAH VRQHNQLLPN LTVRETLAFI AQMRLPRTFS QAQRDKRVED VIAELRLRQC ADTRVGNMYV RGLSGGERRR VSIGVQLLWN PGILILDEPT SGLDSFTAHN LVKTLSRLAK GNRLVLISLH QPRSDIFRLF DLVLLMTSGT PIYLGAAQHM VQYFTAIGYP CPRYSNPADF

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human ABCG8 (NP_071882.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ABCG8 Antikörper (ABIN3022643)

Chen, Wu: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." in: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).

Details zu ABCG8

Target: ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))

Andere Bezeichnung: ABCG8 (ABCG8 Produkte)

Synonyme: DDBDRAFT_0167690 antikoerper, DDBDRAFT_0191232 antikoerper, DDB_0167690 antikoerper, DDB_0191232 antikoerper, zgc:172358 antikoerper, GBD4 antikoerper, STSL antikoerper, 1300003C16Rik antikoerper, AI114946 antikoerper, sterolin-2 antikoerper, ATP binding cassette subfamily G member 8 antikoerper, ATP-binding cassette sub-family G member 8 antikoerper, ABC transporter G family protein antikoerper, ATP-binding cassette, sub-family G (WHITE), member 8 antikoerper, ABCG8 antikoerper, PTRG_02054 antikoerper, abcG8 antikoerper, abcg8 antikoerper, Abcg8 antikoerper

Hintergrund: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.,ABCG8,GBD4,STSL,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,ABCG8

Molekulargewicht: 75 kDa

Gen-ID: 64241

UniProt: Q9H221

Pathways: Lipid Metabolism