ABCG8 Antikörper (Internal Region)
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- Target Alle ABCG8 Antikörper anzeigen
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
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Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCG8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- ABCG8 Antibody detects endogenous levels of total ABCG8.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ABCG8, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ABCG8 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
- Andere Bezeichnung
- ABCG8 (ABCG8 Produkte)
- Synonyme
- DDBDRAFT_0167690 antikoerper, DDBDRAFT_0191232 antikoerper, DDB_0167690 antikoerper, DDB_0191232 antikoerper, zgc:172358 antikoerper, GBD4 antikoerper, STSL antikoerper, 1300003C16Rik antikoerper, AI114946 antikoerper, sterolin-2 antikoerper, ATP binding cassette subfamily G member 8 antikoerper, ATP-binding cassette sub-family G member 8 antikoerper, ABC transporter G family protein antikoerper, ATP-binding cassette, sub-family G (WHITE), member 8 antikoerper, ABCG8 antikoerper, PTRG_02054 antikoerper, abcG8 antikoerper, abcg8 antikoerper, Abcg8 antikoerper
- Hintergrund
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Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Gene: ABCG8
- Molekulargewicht
- 76kDa
- Gen-ID
- 64241
- UniProt
- Q9H221
- Pathways
- Lipid Metabolism
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