Aurora A Antikörper

Produktnummer ABIN289985

Produktdetails anti-Aurora A Antikörper

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: This antibody was purified from rabbit serum by affinity chromatography.

Immunogen: GST-Human Aurora-A fusion Protein

Anwendungsinformationen

Applikationshinweise: Working dilution For western blotting , 0.5-2 ug/mlFor Immunohistochemistry , 1-2ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: Aurora-A (AURKA Produkte)

Synonyme: AIK antikoerper, ARK1 antikoerper, AURA antikoerper, AURORA2 antikoerper, BTAK antikoerper, PPP1R47 antikoerper, STK15 antikoerper, STK6 antikoerper, STK7 antikoerper, AIRK1 antikoerper, AU019385 antikoerper, AW539821 antikoerper, Ark1 antikoerper, Aurora-A antikoerper, Ayk1 antikoerper, IAK antikoerper, IAK1 antikoerper, Stk6 antikoerper, 87A7-9/2 antikoerper, Aur-A antikoerper, AurA antikoerper, CG3068 antikoerper, Dmel\\CG3068 antikoerper, aur-A antikoerper, aurA antikoerper, ck10 antikoerper, ck[10] antikoerper, l(3)87Ac antikoerper, l(3)ck10 antikoerper, ARK-1 antikoerper, Eg2 antikoerper, aik antikoerper, ark1 antikoerper, aur-a antikoerper, aura antikoerper, aurka-a antikoerper, aurora2 antikoerper, btak antikoerper, stk15 antikoerper, stk6 antikoerper, stk7 antikoerper, pEg2 antikoerper, wu:fb37c10 antikoerper, wu:fc02c02 antikoerper, zgc:100912 antikoerper, AURKA antikoerper, aurka antikoerper, aurora kinase A antikoerper, aurora A antikoerper, aurora kinase A L homeolog antikoerper, hypothetical protein antikoerper, aurora kinase A S homeolog antikoerper, AURKA antikoerper, Aurka antikoerper, aurA antikoerper, aurka.L antikoerper, aurka antikoerper, Aurora-A antikoerper, aurka.S antikoerper

Hintergrund: Aurora-A (Aurora-A/STK-15/Aik) encoding a centrosome-associated kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. So that, Aurora-A is a potentialoncogene. Aurora family have been identified three types (Aurora-A, B, C) which has high homologydomain in C terminal region. Aurora family is indispensable kinase that regulate the structure and functionof centrosomes and spindle. Aurora-A could be one of targeting molecule of anti-cancer therapy.This antibody was established from the purified serum of the immunized rabbit with N terminal region ofAurora-A and did not show any cross- reactivity to Aurora-B and Aurora-C. This antibody is useful forwestern blotting and immunohistochemistry.

Pathways: Zellzyklus, Asymmetric Protein Localization