Aurora A Antikörper

Produktnummer ABIN968971

Produktdetails anti-Aurora A Antikörper

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human AURKA expressed in E. coli.

Klon: 1F8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Aurora A Antikörper (ABIN968971)

Veerakumarasivam, Goldstein, Saeb-Parsy, Scott, Warren, Thorne, Mills, Venkitaraman, Neal, Kelly: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).

De Luca, Brunetto, Asteriti, Giubettini, Lavia, Guarguaglini: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA (AURKA Produkte)

Synonyme: AIK antikoerper, ARK1 antikoerper, AURA antikoerper, AURORA2 antikoerper, BTAK antikoerper, PPP1R47 antikoerper, STK15 antikoerper, STK6 antikoerper, STK7 antikoerper, AIRK1 antikoerper, AU019385 antikoerper, AW539821 antikoerper, Ark1 antikoerper, Aurora-A antikoerper, Ayk1 antikoerper, IAK antikoerper, IAK1 antikoerper, Stk6 antikoerper, 87A7-9/2 antikoerper, Aur-A antikoerper, AurA antikoerper, CG3068 antikoerper, Dmel\\CG3068 antikoerper, aur-A antikoerper, aurA antikoerper, ck10 antikoerper, ck[10] antikoerper, l(3)87Ac antikoerper, l(3)ck10 antikoerper, ARK-1 antikoerper, Eg2 antikoerper, aik antikoerper, ark1 antikoerper, aur-a antikoerper, aura antikoerper, aurka-a antikoerper, aurora2 antikoerper, btak antikoerper, stk15 antikoerper, stk6 antikoerper, stk7 antikoerper, pEg2 antikoerper, wu:fb37c10 antikoerper, wu:fc02c02 antikoerper, zgc:100912 antikoerper, AURKA antikoerper, aurka antikoerper, aurora kinase A antikoerper, aurora A antikoerper, aurora kinase A L homeolog antikoerper, hypothetical protein antikoerper, aurora kinase A S homeolog antikoerper, AURKA antikoerper, Aurka antikoerper, aurA antikoerper, aurka.L antikoerper, aurka antikoerper, Aurora-A antikoerper, aurka.S antikoerper

Hintergrund:

Description: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Aliases: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA

Molekulargewicht: 48 kDa

Gen-ID: 6790

HGNC: 6790

Pathways: Zellzyklus, Asymmetric Protein Localization