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NR1H3 Antikörper (C-Term)

NR1H3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856354
  • Target Alle NR1H3 Antikörper anzeigen
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 75
    • 56
    • 45
    • 17
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 83
    • 9
    • 2
    Kaninchen
    Klonalität
    • 77
    • 17
    Polyklonal
    Konjugat
    • 42
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NR1H3 Antikörper ist unkonjugiert
    Applikation
    • 80
    • 31
    • 27
    • 27
    • 26
    • 10
    • 10
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to LXR-alpha (nuclear receptor subfamily 1, group H, member 3)
    LXR alpha antibody [C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LXR alpha. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product NR1H3 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Molt-4

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Andere Bezeichnung
    nuclear receptor subfamily 1 group H member 3 (NR1H3 Produkte)
    Synonyme
    NR1H3 antikoerper, LXR-a antikoerper, LXRA antikoerper, RLD-1 antikoerper, AU018371 antikoerper, LXR antikoerper, RLD1 antikoerper, Unr1 antikoerper, LXRalpha antikoerper, LXR-alpha antikoerper, im:7141239 antikoerper, wu:fd59b01 antikoerper, zgc:113339 antikoerper, zgc:158542 antikoerper, nuclear receptor subfamily 1 group H member 3 antikoerper, nuclear receptor subfamily 1, group H, member 3 antikoerper, NR1H3 antikoerper, nr1h3 antikoerper, Nr1h3 antikoerper
    Hintergrund
    The liver X receptors, LXRA and LXRB (NR1H2, MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs, see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM]

    Cellular Localization: Nucleus
    Molekulargewicht
    50 kDa
    Gen-ID
    10062
    UniProt
    Q13133
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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