NR1H3 Antikörper (AA 1-402)
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- Target Alle NR1H3 Antikörper anzeigen
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Bindungsspezifität
- AA 1-402
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR1H3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NR1H3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Andere Bezeichnung
- NR1H3 (NR1H3 Produkte)
- Synonyme
- NR1H3 antikoerper, LXR-a antikoerper, LXRA antikoerper, RLD-1 antikoerper, AU018371 antikoerper, LXR antikoerper, RLD1 antikoerper, Unr1 antikoerper, LXRalpha antikoerper, LXR-alpha antikoerper, im:7141239 antikoerper, wu:fd59b01 antikoerper, zgc:113339 antikoerper, zgc:158542 antikoerper, nuclear receptor subfamily 1 group H member 3 antikoerper, nuclear receptor subfamily 1, group H, member 3 antikoerper, NR1H3 antikoerper, nr1h3 antikoerper, Nr1h3 antikoerper
- Hintergrund
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Background: Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
Aliases: Liver X receptor alpha antibody, LXR a antibody, LXRA antibody, NR1H3 antibody, NR1H3_HUMAN antibody, Nuclear receptor subfamily 1 group H member 3 antibody, Oxysterols receptor LXR alpha antibody, Oxysterols receptor LXR-alpha antibody, RLD 1 antibody, RLD1 antibody
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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