NFKBIB Antikörper (pSer23) (Alexa Fluor 594)

Produktnummer ABIN2814698

Produktdetails anti-NFKBIB Antikörper (Alexa Fluor 594)

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Bindungsspezifität: pSer23

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKBIB Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NFKBIB around the phosphorylation site of Ser23

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NFKBIB

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Andere Bezeichnung: IKB beta (NFKBIB Produkte)

Synonyme: NFKBIB antikoerper, IKB-beta antikoerper, IKappaBbeta antikoerper, IkB antikoerper, IkBb antikoerper, IKBB antikoerper, TRIP9 antikoerper, NFKB inhibitor beta antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antikoerper, NFKBIB antikoerper, Nfkbib antikoerper

Hintergrund:

Synonyms: IKB beta Ser23, IKB beta S23, p-IKB beta Ser23, p-IKB beta S23, NFKBIBSer23, NFKBIBphospho S23, IkB-betaSer22, IkB beta, NF-kappa-B inhibitor beta, IKB beta, NF-kappa-BIB, TRIP-9, I-kappa-B-beta, IkappaBbeta, IkB-beta, IkB-B, Thyroid receptor-interacting protein 9, TR-interacting protein 9, NFKBIB, IKBB.

Background: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].

Gen-ID: 4793

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades