EPS15 Antikörper (N-Term)
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- Target Alle EPS15 Antikörper anzeigen
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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Bindungsspezifität
- AA 186-216, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPS15 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit Anti-Human EPS15R (N-term) Antibody
- Immunogen
- This EPS15R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human EPS15R.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product EPS15 Primärantikörper
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- Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2.0 mg/mL
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- Target
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Andere Bezeichnung
- EPS15 (EPS15 Produkte)
- Synonyme
- AF-1P antikoerper, AF1P antikoerper, MLLT5 antikoerper, CG16932 antikoerper, Dmel\\CG16932 antikoerper, EH1 antikoerper, EPS-15 antikoerper, Eps15 antikoerper, anon-WO0118547.85 antikoerper, eps-15 antikoerper, eps15 antikoerper, i31 antikoerper, 2410112D09Rik antikoerper, RGD1307641 antikoerper, epidermal growth factor receptor pathway substrate 15 antikoerper, Epidermal growth factor receptor pathway substrate clone 15 antikoerper, hypothetical protein antikoerper, EPS15 antikoerper, Eps-15 antikoerper, eps15 antikoerper, Eps15 antikoerper, PGTG_06574 antikoerper
- Hintergrund
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Target Description: Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.
Gene Symbol: EPS15L1
- Molekulargewicht
- 94255 Da
- Gen-ID
- 58513
- UniProt
- Q9UBC2
- Pathways
- EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
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