C-JUN Antikörper (N-Term)

Produktnummer ABIN487301

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-C-JUN Antikörper wird verwendet zum Nachweis von C-JUN in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Schaf und Hund. Er wurde validiert für WB, IHC und ChIP.

Kurzübersicht für C-JUN Antikörper (N-Term) (ABIN487301)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Schaf, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C-JUN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Produktdetails anti-C-JUN Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: JUN Antibody - N-terminal region

Sequenz: TAKMETTFYD DALNASFLPS ESGPYGYSNP KILKQSMTLN LADPVGSLKP

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against JUN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JUN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-C-JUN Antikörper (ABIN487301)

Russo, Pinsino, Costa, Bonaventura, Matranga, Zito: "The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo." in: The FEBS journal, Vol. 281, Issue 17, pp. 3828-43, (2014) (PubMed).

Details zu C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung: JUN

Hintergrund:

Background Information: JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Jun proto-oncogene

Alternative Symbols: AP1, p39, AP-1, cJUN, c-Jun

Protein Name: Transcription factor AP-1

Molekulargewicht: 36kDa

Gen-ID: 3725

NCBI Accession: NP_002219

UniProt: P05412

Pathways: MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine